November 20, 2024
VIA EDGAR SUBMISSION
U.S. Securities and Exchange Commission
Division of Corporation Finance, Office of Life Sciences
100 F Street, NE
Washington, DC 20549
Attention: Christopher Edwards
| Re: | Climb Bio, Inc. |
Registration Statement on Form S-3
Filed November 12, 2024
File No. 333-283166
Request for Acceleration
Ladies and Gentlemen:
Pursuant to Rule 461 under the Securities Act of 1933, as amended, Climb Bio, Inc. hereby requests acceleration of the effective date of its Registration Statement on Form S-3 (File No. 333-283166), so that it may become effective at 4:30 p.m., Eastern Time, on November 22, 2024, or as soon as practicable thereafter.
Very truly yours,
CLIMB BIO, INC.
| By: | /s/ Aoife Brennan | |
| Name: Aoife Brennan, M.B., Ch.B. | ||
| Title: President and Chief Executive Officer |